152 EXPLORATORY ANALYSIS OF TROPONIN AS BIOMARKER OF ACUTE ISCHAEMIC STROKE SUBTYPES IN A GROUP OF PATIENTS RECRUITED TO THE MIND STUDY

Abstract Background Stroke is a major common cause of acquired disability and death worldwide. Atrial dysfunction or cardiomyopathy, defined by the presence specific serum biomarkers, ECG findings, echocardiographic increases risk atrial fibrillation, which has been implicated as key factor for ischaemic stroke. There now growing body evidence suggests that early positive troponin after stroke may be independently associated with cardiac embolic source. miRNA Novel Diagnostic biomarker (MiND) current Irish-led research study whose aim to discover unique highly diagnostic prognostic expressed in acute Methods Data were retrospectively extracted from patients recruited MiND confirmed diagnosis within 12 hours symptoms onset having also undergone high-sensitivity testing July 2019 November 2021. subtypes classified per ESUS criteria. Statistical analysis was carried out using STATA/SE, version 16.0. Results We identified 52 who had performed onset. Twenty-two cardioembolic (CE), 17 non-cardioembolic (NCE) 13 Embolic unknown source (ESUS). The mean age each group 77.5 (±9.8), 65.5 (±12.8) 66.3 (±11.7) years, respectively. rate positivity 55% (12/22), 29% (5/17) 15% (2/13), unadjusted logistic revealed association between CE subtype elevated (OR 3.94, 95% 1.20-12.98, p = 0.024) an inverse 0.24, CI 0.05-1.21, 0.083). Conclusion Our reveals strong predictor but not subtype.